014650
25-Hydroxy Vitamin D3 3-Sulfate Sodium Salt
Size
£687.00
- SKU:
- 014650
- Molecular Weight:
- 502.68
- Storage Conditions:
- -70°C
- Supplier:
- United States Biological
- Extra Details:
- 25-Hydroxyvitamin D3 3-Sulfate is a metabolite of 24,25-Dihydroxyvitamin D3 and 25-Hydroxyvitamin D3. Calcifediol (INN), also known as calcidiol, 25-hydroxycholecalciferol, or 25-hydroxyvitamin D (abbreviated 25(OH)D), is a prehormone that is produced in the liver by hydroxylation of vitamin D3 (cholecalciferol) by the enzyme cholecalciferol 25-hydroxylase which was isolated by Michael F. Holick. Physicians worldwide measure this metabolite to determine a patient's vitamin D status. At a typical daily intake of vitamin D3, its full conversion to calcifediol takes approximately 7 days. Calcifediol is then converted in the kidneys (by the enzyme 25(OH)D-1α-hydroxylase) into calcitriol (1,25-(OH)2D3), a secosteroid hormone that is the active form of vitamin D. It can also be converted into 24-hydroxycalcidiol in the kidneys via 24-hydroxylation. Synonyms: (3β,5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-3,25-diol 3-(Hydrogen Sulfate) Sodium Salt; 25-Hydroxyvitamin D3 3-Sulfate Sodium Salt; 25-Hydroxyvitamin D3 3β-Sulfate Sodium Salt; Calcifediol 3-Sulfate Sodium Salt CAS No: Free acid: 99447-30-0 Molecular Formula: C₂₇H₄₃NaO₅S Molecular Weight: 502.68 Purity: ≥90% Appearance: Pale yellow to beige solid Solubility: Methanol (Slightly), Water (Slightly) Method for Determining identity: Proton NMR Spectroscopic and Mass Spectrometric Analysis Melting Point: 104-108°C (dec.) (lit) Atmosphere: Inert Gas Storage and Stability: Long-term storage is recommended at -70°C. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Hygroscopic, Light sensitive and temperature sensitive. Store under inert atmophere.
- Shipping Conditions:
- Dry Ice