Crenolanib

Size

£448.00

SKU:: 007102
Molecular Weight:: 443.54
Storage Conditions:: RT
Supplier:: United States Biological
CAS Number:: 670220-88-9
Format:: White to Off-White Solid
Extra Details:: Crenolanib is a tyrosine kinase inhibitor that acts by specifically inhibiting the receptor tyrosine kinases PDGFRα and PDGFRβ. Crenolanib inhibits the activity of PDGFRα D842V kinase and prevented the phosphorylation of wild type PDGFRα. Crenolanib possesses potential antineoplastic activity. Crenolanib is believed to suppress PDGFR-related signal transduction pathways leading to the inhibition of tumor angiogenesis and tumor cell proliferation. Form: White to Off-White Solid Melting Point: 217-220°C Solubility: DMSO, Methanol