003780
Benzo[a]pyrene Diol Epoxide (BPDE)
Size
£696.00
- SKU:
- 003780
- Molecular Weight:
- 302.32
- Storage Conditions:
- 4°C
- Supplier:
- United States Biological
- CAS Number:
- 58917-67-2
- Extra Details:
- Benzo[a]pyrene diol epoxide stimulates an inflammatory response in normal human lung fibroblasts through a p53 and JNK mediated pathway. Benzo [a]pyrene diol epoxide (BPDE), a carcinogen present in tobacco smoke as well as in environmental pollution, induces esophageal carcinogenesis. Synonyms: (7R,8S,8aS,9aR)-rel-7,8,8a,9a-Tetrahydrobenzo[10,11]chryseno[3,4-b]oxirene-7,8-diol; (7α,8β,8aα,9aα)-7,8,8a,9a-Tetrahydrobenzo[10,11]chryseno[3,4-b]oxirene-7,8-diol; (±)-7α,8β-Dihydroxy-9β,10β-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene; (±)-7β,8α-Dihydroxy-9α,10α-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene; (±)-anti-BPDE; anti-Benzo[a]pyrene-7,8-diol-9,10-epoxide; trans-7,8-Dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene CAS Number: 58917-67-2 Molecular Weight: 302.32 Molecular Formula: C₂₀H₁₄O₃ Purity: ≥95% Appearance: Pale yellow to yellow solid Melting Point: 164-166°C Solubility: DMSO (Slightly) Method for Determining Identity: Proton NMR (DMSO-d6) Spectroscopic and Mass Spectrometric Analysis TLC Conditions: C18: Isopropanol: ammonium = 9.5:0.5. Visualized with UV and AMCS; Single spot, Rf=0.65 Storage and Stability: Powder is stable for 6 months after receipt at 4°C. Hygroscopic. Under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- Shipping Conditions:
- Ambient