Auranofin

Size

£320.00

SKU:: 002985
Molecular Weight:: 678.48
Purity:: As reported
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 34031-32-8
Format:: White to off-white crystalline powderWhite to off-white crystalline powder
Extra Details:: Auranofin is a new oral gold-based antiarthritis drug. Auranofin inhibits various leukocyte activation pathways at multiple sites. Auranofin inhibits the release of inflammatory mediators from human macrophages, basophils, and pulmonary mast cells. Auranofin is an efficient inducer of mitochondrial membrane permeability transition pore in the presence of calcium ions related to its inhibition of mitochondrial thioredoxin reductase. Synonyms: (S)-Triphenylphosphine gold(I) 2,3,4,6-tetra-O-acetyl-b-D-thioglucopyranoside; 1-Thio-b-D-glucopyranosatotriethylphosphine gold-2,3,4,6-tetraacetate; 3,4,5-Triacetyloxy-6-(acetyloxymethyl) oxane-2-thiolate triethylphosphanium CAS No: 34031-32-8 Molecular Formula: C₂₀H₃₄AuO₉PS Molecular Weight: 678.48 Appearance: White to off-white crystalline powder Assay (Gold content): 28-31% Specific Optical Rotation[α]20 (c=1, CHCl): -40 to -58° Melting Point: 110-118°C Solubility: Chloroform (Slightly), Methanol (Slightly) Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. Stable for 6 months ater receipt.