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001807

17-(Allylamino) Geldanamycin

Size

£288.00

SKU:
001807
Molecular Weight:
585.69
Purity:
≥98%
Storage Conditions:
-20°C
Supplier:
United States Biological
CAS Number:
75747-14-7
Format:
Supplied as a dark purple to very dark red powder.
Extra Details:
Potent inhibitor of heat shock protein 90 (Hsp90). 17-AAG is a less toxic analog than Geldanamycin. It induces apoptosis and displays antitumor effects. 17-AAG inhibits the activity of oncogenic proteins such as N-ras, Ki-ras, c-Akt, and p185erB2. Synonyms: 17-Demethoxy-17-(2-propenylamino)geldanamycin; 17-(Allylamino)-17-demethoxygeldanamycin; 17-(Allylamino)-17-desmethylgeldanamycin; 17-Demethoxy-17-allylaminogeldanamycin; 17AAG; CP 127374; KOS 953; NSC 330507; Tanespimycin; 17-AAG CAS Number: 75747-14-7 Molecular Formula: C₃₁H₄₃N₃O₈ Molecular Weight: 585.69 Appearance: Supplied as a dark purple to very dark red powder. Melting Point: >194°C (dec.) Solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) Storage and Stability: Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Shipping Conditions:
Blue Ice