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001674

S-(5'-Adenosyl)-L-Methionine-d3 Disulfate Salt (Mixture of Diastereomers)

Size

£740.00

SKU:
001674
Molecular Weight:
597.61
Purity:
≥95% Chemical, ≥98% Isotopic
Storage Conditions:
-20°C
Supplier:
United States Biological
Format:
White to pale yellow solid
Extra Details:
Labeled S-(5’-Adenosyl)-L-methionine. Methyl donor; cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). Although present in all cells, it is concentrated in liver where 85% of all methylation reactions occur. It is also involved in regulating liver function, growth, and response to injury. Synonyms: 5’-[[(3S)-3-Amino-3-carboxypropyl](methyl-d3)sulfonio]-5’-deoxyadenosine Disulfate; 5’-[(L-3-Amino-3-carboxypropyl)(methyl-d3)sulfonio]-5’-deoxyadenosine Disulfate; S-Adenosylmethionine-d3 Disulfate; Active Methionine-d3 Disulfate; Ademetionine-d3 Disulfate; L-S-Adenosylmethionin-d3 Disulfate; S-Adenosyl-L-methionine-d3 Disulfate Molecular Formula: C₁₅H₂₃D₃N₆O₁₃S₃ Molecular Weight: 597.61 Appearance: White to pale yellow solid Purity: ≥95% Chemical, ≥98% Isotopic Melting Point: >102°C (dec.) Solubility: Water (Slightly) Method for Determining Identity: Proton NMR spectroscopic analysis and Mass spectrometric analysis TLC Conditions: C18; Methanol: Water: Acetic Acid=5:5:0.02; Visualized with UV and KMnO4; Rf=0.40 Elemental Analysis: Calculated: %C: 30.15, %H: 4.39, %N: 14.06 Normalized Intensity: As Reported Sulfate Content (Ion Chromatography): ~33% Water Content (Elemental Analysis): ~3% Storage and Stability: Store at -20°C under an atmosphere of inert gas. Stable for 6 months after receipt. Caution: Hygroscopic.
Shipping Conditions:
Blue Ice