0004-01A

4-1BB ligand, aa71-254, Recombinant, Human, His-Tag (4-1BBL, CD137L, TNFSF9, Tumor necrosis factor ligand superfamily member 9)

Size

£586.00

SKU:: 0004-01A
Molecular Weight:: 23.8
Purity:: ≥ 95% by SDS-PAGE
Storage Conditions:: -70°C
Supplier:: United States Biological
Format:: Supplied as liquid in 20 mM Tris-HCl buffer (pH 8.0) containing 100mM NaCl, 20% glycerol.
Extra Details:: 4-1BB ligand is a type 2 transmembrane glycoprotein belonging to the TNF superfamily. 4-1BBL is expressed by activated B cells, macrophages, dendritic cells, activated T cells, neurons and astrocytes. The interaction of 4-1BB with 4-1BBL strongly regulates immunity and has been proposed to preferentially control T cell responses based on studies in various murine models of cancer, infectious disease and autoimmune disease. Purified by using conventional chromatography. Source: Recombinant human 4-1BB ligand, fused to His-tag at N-terminus, was expressed in E.coli. Molecular Weight: 23.8kD (222aa) Sequence of amino acids: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMRE GPELSPDDPA GLLDLRQGMF AQLVAQNVLL IDGPLSWYSD PGLAGVSLTG GLSYKEDTKE LVVAKAGVYY VFFQLELRRV VAGEGSGSVS LALHLQPLRS AAGAAALALT VDLPPASSEA RNSAFGFQGR LLHLSAGQRL GVHLHTEARA RHAWQLTQGA TVLGLFRVTP EIPAGLPSPR SE Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, aliquot to avoid repeated freezing and thawing and freeze at 20 or 70°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.