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  2. Polyclonal

GP26

Anti-Cingulin, Meerschweinchen polyklonal

Cannot supply to this region.

SKU:
GP26
Additional Names:
Cingulin, CGN, KIAA1319
Application:
IHC, WB, IF, ICC
Purification:
Stabilized antiserum
Storage Conditions:
Please refer to datasheet
Supplier:
Progen
Host:
Guinea Pig
Reactivities:
Bovine, Human, Mouse, Rabbit
ABP:
IMP-GEN-14-02 < 3%
Immunogen:
Full length GST-fusion protein of human cingulin
Formulation:
Contains 0.09% sodium azide and 0.5% BSA
Uniprot:
P23805, P59242, Q9P2M7
Synonyms:
BC;cingulin;conglutinin;conglutinin 1
Extra Details:
The antibody reacts specifically with cingulin (a ca.150 kD polypeptide) present in tight junctions (zonula occludens) of polar epithelia (e.g. colon, duodenum, kidney, liver, pancreas) of transitional epithelia (e.g. bladder epithelium) and of stratified epithelia (e.g. skin, foot sole, tongue, oesophagus, vagina). It is negative with endothelia of vessels and capillaries (e.g. in heart and brain). Polypeptide reacting: Cingulin, a polypeptide of 126.5 kD (calculated from aa sequence data); apparent Mr 150 kD (after SDS-PAGE); pI 6.5 (very similar to that of symplekin, another junctional protein). Reactivity on cultured cell lines: Carcinoma cell lines of human(e.g. MCF-7, Caco-2, PLC, A-431), bovine (MDBK, BMGE) and canine (MDCK) origin. Positive control: total cell lysate of e.g. CaCo-2 cells.
Shipping Conditions:
Blue Ice