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691602

anti-CD71, EBS-CD-040, mouse monoclonal antibody

Cannot supply to this region.

SKU:
691602
Additional Names:
Transferrin receptor protein 1, TR, TfR, TfR1, Trfr, T9, p90, CD antigen CD71 [Cleaved into: Transferrin receptor protein 1, serum form, sTfR], TFRC
Application:
Flow Cytometry, IHC, WB, IF, ICC
Concentration:
100 ug/ml
Purification:
Affinity Purified
Storage Conditions:
Please refer to datasheet
Supplier:
Progen
Host:
Mouse
Reactivities:
Human
ABP:
No Import Docs
Immunogen:
Human thymocytes
Formulation:
PBS with 0.02% sodium azide
Clone:
EBS-CD-040
Uniprot:
P02786
Synonyms:
CD71;IMD46;p90;T9;TFR;TFR1;TR;transferrin receptor protein 1;TRFR
Extra Details:
The transferrin receptor is a type II membrane glycoprotein existing as a homodimer of 180-190 kDa with interchain disculphide bonding. The ligand is the serum iron transport protein transferrin. CD71 is expressed weakly on all resting leucocytes, but is upregulated on all cells upon activation, reflecting the iron dependence of proliferation. In other tissues CD71 is expressed on most dividing cells, but also strongly on brain endothelium and alveolar macrophage. CD71 expression can reflect clinical behaviour or response to therapy in a number of malignancies including leukemia, lymphoma and breast cancer. Positive control: CCRF-CEM, Jurkat, K-562, human placenta, breast carcinoma.
Shipping Conditions:
Blue Ice