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691601

anti-CD70, EBS-CD-039, mouse monoclonal antibody

Cannot supply to this region.

SKU:
691601
Additional Names:
CD70 antigen, CD27 ligand, CD27-L, Tumor necrosis factor ligand superfamily member 7, CD antigen CD70, CD70, CD27L, CD27LG, TNFSF7
Application:
ELISA, Flow Cytometry, IHC, IF, ICC, IP
Concentration:
100 ug/ml
Purification:
Affinity Purified
Storage Conditions:
Please refer to datasheet
Supplier:
Progen
Host:
Mouse
Reactivities:
Human
ABP:
No Import Docs
Immunogen:
Human WM-1 (Waldenstrom's macroglobulinemia) cells
Formulation:
PBS with 0.02% sodium azide
Clone:
EBS-CD-039
Uniprot:
P32970
Synonyms:
CD27 ligand;CD27-L;CD27L;CD27LG;CD70 antigen;Ki-24 antigen;LPFS3;surface antigen CD70;TNFSF7;TNLG8A;tumor necrosis factor ligand 8A;tumor necrosis factor ligand superfamily member 7
Extra Details:
CD70 is a 30 kDa cytokine that belongs to the tumor necrosis factor (TNF) ligand family. CD70 is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T- and B-lymphocytes. It induces proliferation of co-stimulated T-cells, enhaces the generation of cytolytic T-cells, and constributes to T-cell activation. It futher plays a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis. EBS-CD-039 blocks the interaction between CD27 and CD70, and has been shown to inhibit T-cell proliferation induced by dendritic cells. Positive control: Raji cells, lymph node or tonsil.
Shipping Conditions:
Blue Ice