691598
anti-CD61, EBS-CD-034, mouse monoclonal antibody
Cannot supply to this region.
- SKU:
- 691598
- Additional Names:
- Integrin beta-3, Platelet membrane glycoprotein IIIa, GPIIIa, CD antigen CD61, ITGB3, GP3A
- Application:
- Flow Cytometry, IHC, IF, ICC
- Concentration:
- 100 ug/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Progen
- Host:
- Mouse
- Reactivities:
- Human
- ABP:
- No Import Docs
- Immunogen:
- Stimulated human PBMC's
- Formulation:
- PBS with 0.02% sodium azide
- Clone:
- EBS-CD-034
- Uniprot:
- P05106
- Synonyms:
- antigen CD61;BDPLT16;BDPLT2;BDPLT24;CD61;GP3A;GPIIIa;GT;GT2;integrin beta 3;integrin beta chain, beta 3;integrin beta-3;integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61);platelet membrane glycoprotein IIIa
- Extra Details:
- EBS-CD-034 reacts with a complex of CD41 and CD61, i.e. alpha IIb integrin and the integrin beta chain. The MW of the GPIIIa is 105 kDa unreduced and 90 kDa reduced. The integrin beta 3 chain can also form a complex called the vitronectin receptor with integrin alpha V: the CD51/CD61 complex. Ligands are fibrinogen, fibronectin, von Willebrand factor, vitronectin and thrombospondin. Residues 237-248 of GPIIIa or CD61 are critical in adhesive protein binding. The CD51/CD61 complex is also found on endothelial cells, some B-cells, monocytes/macrophages and tumor cells. Positive control: U937, KG1a, HEL cells, human platelets in lymph nodes or tonsils.
- Shipping Conditions:
- Blue Ice