691583
anti-CD43b, Bra7G, mouse monoclonal antibody
Cannot supply to this region.
- SKU:
- 691583
- Application:
- Flow Cytometry, IHC, WB, IF, ICC
- Concentration:
- 100 ug/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Progen
- Host:
- Mouse
- Reactivities:
- Human
- ABP:
- No Import Docs
- Immunogen:
- Immature pluripotent human leukemia K562 cells
- Formulation:
- PBS with 0.02% sodium azide
- Clone:
- Bra7G
- Extra Details:
- Bra7G reacts with a 95/115 kDa protein on T-cells and thymocytes and a 115/135 kDa molecule on neutrophils and platelets. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma. In addition, expression is altered in Wiskott Aldrich Syndrome. A proportion of AIDS patients have antibodies to CD43. A soluble form called galactoglycoprotein is present in serum. Bra7G was typed at the 5th International Workshop on Human Leucocyte Differentiation antigens. Positive control: paracortex in a tonsil or a reactive lymph node.
- Shipping Conditions:
- Blue Ice