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691558

anti-CD10, CB-CALLA, mouse monoclonal antibody

Cannot supply to this region.

SKU:
691558
Additional Names:
Neprilysin, EC 3.4.24.11, Atriopeptidase, Common acute lymphocytic leukemia antigen, CALLA, Enkephalinase, Neutral endopeptidase 24.11, NEP, Neutral endopeptidase, Skin fibroblast elastase, SFE, CD antigen CD10, MME, EPN
Application:
Flow Cytometry, IHC, IF, ICC
Concentration:
100 ug/ml
Purification:
Affinity Purified
Storage Conditions:
Please refer to datasheet
Supplier:
Progen
Host:
Mouse
Reactivities:
Human
ABP:
No Import Docs
Immunogen:
Human PBLs
Formulation:
PBS with 0.02% sodium azide
Clone:
CB-CALLA
Uniprot:
P08473
Synonyms:
atriopeptidase;CALLA;CD10;CMT2T;common acute lymphocytic leukemia antigen;Enkephalinase;membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10);membrane metallo-endopeptidase variant 1;membrane metallo-endopeptidase variant 2;NEP;neprilysin;neprilysin-390;neprilysin-411;neutral endopeptidase 24.11;SCA43;SFE;skin fibroblast elastase
Extra Details:
CB-CALLA reacts with CD10 or CALLA, a cell surface enzyme with neutral metalloendopeptidase activity, inactivating a variety of biologically active peptides. CD10 is a 100 kDa glycoprotein, expressed on 70% of pre-B ALL cells (common ALL), but also on early lymphoid progenitor cells in bone marrow and fetal liver. Other normal CD10 positive tissues include renal epithelium, fibroblasts and germinal centre B-cells. Density of CD10 antigen has been shown to be related to cell differentiation and may have prognostic value for B-cell lineage acute leukemia. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells. Positive control: Raji cells, tonsil, small intestine or kidney.
Shipping Conditions:
Blue Ice