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691556

anti-CD8a,143-44, mouse monoclonal antibody

Cannot supply to this region.

SKU:
691556
Additional Names:
T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2, CD antigen CD8a, CD8A, MAL
Application:
Flow Cytometry, IHC, IF, ICC
Concentration:
100 ug/ml
Purification:
Affinity Purified
Storage Conditions:
Please refer to datasheet
Supplier:
Progen
Host:
Mouse
Reactivities:
Human
ABP:
No Import Docs
Immunogen:
Human PBL
Formulation:
PBS with 0.02% sodium azide
Clone:
143-44
Uniprot:
P01732
Synonyms:
CD8;CD8 antigen, alpha polypeptide (p32);Leu2;Leu2 T-lymphocyte antigen;OKT8 T-cell antigen;p32;T cell co-receptor;T-cell antigen Leu2;T-cell surface glycoprotein CD8 alpha chain;T-lymphocyte differentiation antigen T8/Leu-2;T8 T-cell antigen
Extra Details:
143-44 recognizes a protein of 32 kDa, identified as CD8a. The CD8 molecule consists of alpha and beta chains, which are disulphide-linked into heterodimers or homodimers. CD8 is expressed on a T-cell subset (cytotoxic/suppressor T-cells), thymocytes and NK-cells. The majority of CD8+ T-cells express CD8 as a heterodimer. Some subpopulations of CD8+ T-cells as well as NK-cells may express it as a homodimer. CD8 functions as a co-receptor in concert with TCR for binding the MHC class I/peptide complex. The HIV-2 envelope glycoprotein binds CD8 alpha chain, but not beta chain. 124-1D1 was assigned at the IVth International Workshop. Positive control: TuT78 or hPBL, tonsil.
Shipping Conditions:
Blue Ice