651140
anti-OATP2/OATP8 (Maus, monoklonal, Klon mMDQ)
Cannot supply to this region.
- SKU:
- 651140
- Additional Names:
- Solute carrier organic anion transporter family member 1B1, Liver-specific organic anion transporter 1, LST-1, OATP-C, Sodium-independent organic anion-transporting polypeptide 2, OATP-2, Solute carrier family 21 member 6, SLCO1B1, LST1, OATP1B1, OATP2, OATPC, SLC21A6,Solute carrier organic anion transporter family member 1B3, Liver-specific organic anion transporter 2, LST-2, Organic anion transporter 8, Organic anion-transporting polypeptide 8, OATP-8, Solute carrier family 21 member
- Application:
- IHC, WB, IF, ICC, IP
- Purification:
- Hybridoma cell culture supernatant
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Progen
- Host:
- Mouse
- Reactivities:
- Human
- Immunogen:
- Synthetic N-terminus (24 aa) of human organic anion transporter OATP2
- Formulation:
- Contains 0.09% sodium azide
- Clone:
- mMDQ
- Uniprot:
- Q9NPD5, Q9Y6L6
- Synonyms:
- HBLRR;liver-specific organic anion transporter 1;liver-specific organic anion transporter 2;liver-specific organic anion transporter 3TM13;LST-1;LST-2;LST-3TM13;LST1;LST3;OATP-2;OATP-8;OATP-C;OATP1B1;OATP1B3;OATP2;OATP8;OATPC;organic anion transporter 8;organic anion transporter LST-3c;organic anion-transporting polypeptide 8;SLC21A6;SLC21A8;sodium-independent organic anion-transporting polypeptide 2;solute carrier family 21 (organic anion transporter), member 6;solute carrier family 21 (organic anion transporter), member 8;Solute carrier family 21 member 6;Solute carrier family 21 member 8;solute carrier organic anion transporter family member 1B1;solute carrier organic anion transporter family member 1B3
- Extra Details:
- In Western blot analyses of basolateral membrane fractions of human liver the monoclonal antibody mMDQ reacts with 90 kDa and 120 kDa proteins (after SDS-PAGE) representing OATP2 (also described as OATP-C) and OATP8, respectively. According to a recent new nomenclature these hepatocyte-specific proteins are identical to OATP1B1 and OATP1B3, respectively (Hagenbuch et al., 2003). Using immunofluorescence microscopy mMDQ stains the sinusoidal (basolateral) membranes in frozen sections of human liver, hepatocellular carcinoma (Cui et al., 2003). Tested reactivities on cultured cell lines: transfected HEK293 cells; negative with HepG2 and PLC. Polypeptide reacting: OATP2 and OATP8, human organic anion transporters (90 kDa, 120 kDa, after SDS-PAGE). Hagenbuch, B. & Meier, P. J. The superfamily of organic anion transporting polypeptides. Biochim. Biophys. Acta 1609, 1-18 (2003). Cui, Y. et al. Detection of the human organic anion transporters SLC21A6 (OATP2) and SLC21A8 (OATP8) in liver and hepatocellular carcinoma. Lab. Invest. 83, 527-38 (2003).
- Shipping Conditions:
- Blue Ice