651122
anti-Cingulin (Maus, monoklonal, Klon 139.3.4)
Cannot supply to this region.
- SKU:
- 651122
- Additional Names:
- Cingulin, CGN, KIAA1319
- Application:
- IHC, WB, IF, ICC
- Purification:
- Hybridoma cell culture supernatant
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Progen
- Host:
- Mouse
- Reactivities:
- Bovine, Human, Mouse
- ABP:
- IMP-GEN-2015-06 < 10% Serum <100ml
- Immunogen:
- Synthetic peptide (aa. 4-24)
- Formulation:
- Contains 0.09% sodium azide
- Clone:
- 139.3.4
- Uniprot:
- P23805, P59242, Q9P2M7
- Synonyms:
- BC;cingulin;conglutinin;conglutinin 1
- Extra Details:
- The mab reacts specifically with cingulin (a 150 kDa polypeptide) present in tight junctions (zonula occludens) of polar epithelia (e.g. colon, duodenum, kidney, liver, pancreas), of transitional epithelia (e.g. bladder epithelium), and of stratified epithelia (e.g. skin, foot sole, tongue, oesophagus, vagina). Negative with endothelia of vessels and capillaries (e.g. in heart and brain). Polypeptide reacting: Cingulin, 126.5 kDa polypeptide (calculated from aa sequence data); apparent Mr 150 kDa (after SDS-PAGE); pI 6.5 (very similar to symplekin, another junctional protein). Reactivity on cultured cell lines: Carcinoma cell lines (e.g. MCF-7, Caco-2, PLC, A-431), SV80 (fibroblasts), Glioma; MDBK, MDCK, BMGE.
- Shipping Conditions:
- Blue Ice