651100
anti-Symplekin (Maus, monoklonal, Klon Sym-TJ-E150
Cannot supply to this region.
- SKU:
- 651100
- Additional Names:
- Symplekin, SYMPK, SPK
- Application:
- IHC, WB
- Purification:
- Hybridoma cell culture supernatant
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Progen
- Host:
- Mouse
- Reactivities:
- Human, Rat
- ABP:
- IMP-GEN-2015-06 < 10% Serum <100ml
- Immunogen:
- Human symplekin
- Formulation:
- Contains 0.09% sodium azide
- Clone:
- Sym-TJ-E150
- Uniprot:
- Q92797
- Synonyms:
- Pta1;SPK;SYM;symplekin
- Extra Details:
- The mab reacts specifically with symplekin (a 150 kDa polypeptide) present in 1) tight junctions (zonula occludens) of polar epithelia and Sertoli cells of testis (but not their vascular endothelia!) and 2) exclusively in the nucleoplasm of these and many other cell types which do not form tight junctions (e.g. stratified epithelia such as oesophagus, tongue mucosa, epidermis; squamous cell carcinoma; non-epithelia such as fibroblasts, endothelia, lymphocytes). Polypeptide reacting: symplekin, 126.5 kDa polypeptide (calculated from aa sequence data); apparent Mr 150 kDa (after SDS-PAGE); pI 6.5. Reactivities on cultured cell lines: carcinoma cell lines (e.g. MCF-7, Caco-2, HT29, PLC), SV80 (fibroblasts), U333 CG/343 MG (glioma), K 562 (erythroleukemia), RVF (rat vascular smooth muscle cells).
- Shipping Conditions:
- Blue Ice