65012
anti-Synaptophysin (Maus, monoklonal, Klon SY38)
Cannot supply to this region.
- SKU:
- 65012
- Additional Names:
- Synaptophysin, Major synaptic vesicle protein p38, SYP
- Application:
- IHC, WB, IF, ICC
- Purification:
- Affinity Purified
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Progen
- Host:
- Mouse
- Reactivities:
- Bovine, Human, Mouse, Rat
- ABP:
- IMP-GEN-14-02 < 3%
- Immunogen:
- Synaptophysin from presynaptic vesicles, prepared from bovine brain
- Formulation:
- PBS pH 7.4 with 0.5% BSA and 0.09% sodium azide
- Clone:
- SY38
- Uniprot:
- P07825, P08247, P20488, Q62277
- Synonyms:
- A230093K24Rik;AI848995;BM89 antigen;major synaptic vesicle protein P38;MRX96;MRXSYP;p3;p38;S;Syn;synaptophysin;Syp I;Syp1;XLID96
- Extra Details:
- SY38 represents an excellent marker for several neuroendocrine, neuronal and adrenal tumors. Neuronal and adrenal tumors such as pheochromocytomas, paragangliomas, neuroblastomas, ganglioneuroblastomas. Neuroendocrine tumors of epithelial origin: Pancreatic islet cell carcinoma, bronchial and gastrointestinal carcinoids, medullary carcinoma of thyroid. Polypeptide reacting: 38 kDa transmembrane glycoprotein of presynaptic vesicles. SY38 binds to a cytoplasmatic domain of synaptophysin. The epitope was located to a flexible segment in the center of the repeat structure (Knaus and Betz, 1990). Tested cultured cell lines: rat PC-12 cell line. Knaus, P. & Betz, H. Mapping of a dominant immunogenic region of synaptophysin, a major membrane protein of synaptic vesicles. FEBS Lett. 261, 358-360 (1990).
- Shipping Conditions:
- Blue Ice