61031
anti-Keratin K5/K8 (Pan Epithelial) (Maus, monokl
Cannot supply to this region.
- SKU:
- 61031
- Additional Names:
- Keratin, type II cytoskeletal 74, Cytokeratin-74, CK-74, Keratin-5c, K5C, Keratin-74, K74, Type II inner root sheath-specific keratin-K6irs4, Type-II keratin Kb37, KRT74, K6IRS4, KB37, KRT5C, KRT6IRS4, Keratin, type II cytoskeletal 8, Cytokeratin-8, CK-8, Keratin-8, K8, Type-II keratin Kb8, KRT8, CYK8
- Application:
- IHC, WB, IF, ICC
- Concentration:
- 50 ug/ml
- Physical State:
- Lyophilized
- Purification:
- Affinity Purified
- Storage Conditions:
- 2-8[o]C reconstituted. Aliquot. Avoid freeze/thaw cycles., -20[o]C reconstituted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Progen
- Host:
- Mouse
- Reactivities:
- Bovine, Human, Mouse, Rat
- ABP:
- IMP-GEN-14-02 < 3%
- Immunogen:
- Human keratin K8, purified from SDS PAGE gel
- Formulation:
- Lyophilized; reconstitute in 1 ml dist. water (final solution contains 0.09% sodium azide, 0.5% BSA in PBS buffer, pH 7.4)
- Clone:
- Ks 5+8.22/C22
- Uniprot:
- P05786, P05787, P11679, Q5XQN5, Q7RTS7, Q922U2
- Synonyms:
- 3300001P10Rik;58 kDa cytokeratin;AA960620;ADWH;AL022697;AU019895;AW146334;Car;CARD2;CK-5;CK-74;CK-8;CK5;CK8;CYK8;cytokeratin 5;cytokeratin 8;cytokeratin endo A;cytokeratin-5;cytokeratin-74;cytokeratin-8;cytokeratin-A;En;EndoA;HTSS2;HYPT3;K2C8;K5;K5C;K6IRS4;K74;K8;KERA;keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types);keratin 5c;keratin 6 irs4;keratin 74, type II;keratin 8, type II;keratin complex 2, basic, gene 5;keratin complex 2, basic, gene 8;Keratin-5;Keratin-5c;Keratin-74;Keratin-8;keratin, type II cytoskeletal 5;keratin, type II cytoskeletal 60 kDa, component III;keratin, type II cytoskeletal 74;keratin, type II cytoskeletal 8;KO;Krt-2.;Krt-2.8;Krt2-;Krt2-5;Krt2-8;KRT5C;KRT6IRS4;Tfi;Tfip8;tuftelin interacting protein 8;type II inner root sheath-specific keratin-K6irs4;type-II keratin Kb37;type-II keratin Kb5;type-II keratin Kb8
- Extra Details:
- C22 represents an excellent marker for distinguishing carcinomas from all non-epithelial tumors. The antibody specifically reacts with keratins K5 and K8 present in nearly all epithelia. Polypeptide reacting: Mr 52,500, Mr 58,000 keratins (type II keratins K5 and K8; formerly also designated cytokeratins 5 and 8) of human epithelial cells. Epitope has been mapped to aa 353-367 on alpha helical rod domain of Keratin K8 (Waseem et al., 2004). Reactivity on cultured cell lines: MCF-7, RT 112, HT-29, HaCaT, Detroit 562, RPMI 2650, SSC-12, bovine BMGE+H, BMGE-H, MDBK. Waseem A, Karsten U, Leigh IM, Purkis P, Waseem NH, Lane BE: Conformational changes in the rod domain of human keratin 8 following heterotypic association with keratin 18 and its implication for filament stability. Biochemistry 43, 1283-1295 (2004).
- Shipping Conditions:
- Blue Ice