61003
anti-Desmoplakin 1/2 (Maus, monoklonal, Klon DP-2.
Cannot supply to this region.
- SKU:
- 61003
- Additional Names:
- Desmoplakin, DP, 250/210 kDa paraneoplastic pemphigus antigen, DSP
- Application:
- IHC, WB, IF, ICC
- Concentration:
- 50 ug/ml
- Physical State:
- Lyophilized
- Purification:
- Affinity Purified
- Storage Conditions:
- 2-8[o]C reconstituted. Aliquot. Avoid freeze/thaw cycles., -20[o]C reconstituted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Progen
- Host:
- Mouse
- Reactivities:
- Bovine, Human, Mouse, Rat
- ABP:
- IMP-GEN-14-02 < 3%
- Immunogen:
- Bovine desmoplakin 1 + 2
- Formulation:
- Lyophilized; reconstitute in 1 ml dist. water (final solution contains 0.09% sodium azide, 0.5% BSA in PBS buffer, pH 7.4)
- Clone:
- DP1 + 2-2.15
- Uniprot:
- E9Q557, P15924
- Synonyms:
- 2300002E22Rik;250/210 kDa paraneoplastic pemphigus antigen;5730453H04Rik;AA407887;AA407888;AW109828;D;DCWHKTA;desmoplakin;desmoplakin I/II;desmosomal cytoskeletal connector molecule;DP;r;rul
- Extra Details:
- DP1 + 2-2.15 shows distinct punctate membrane staining of different epithelia. Tumors specifically detected: primary and metastatic carcinoma and meningioma. Polypeptides reacting: Desmoplakin 1 and 2 (Mr 250,000 and 215,000).The epitope recognized by clone DP1 + 2-2.15 is mapped to the N-terminus of the rod domain (Bornslaeger, E. A., 1996). Bornslaeger, E. A. Breaking the connection: displacement of the desmosomal plaque protein desmoplakin from cell-cell interfaces disrupts anchorage of intermediate filament bundles and alters intercellular junction assembly. J. Cell Biol. 134, 985-1001 (1996).
- Shipping Conditions:
- Blue Ice