490947
anti-mTOR (Kaninchen, polyklonal)
Cannot supply to this region.
- SKU:
- 490947
- Additional Names:
- Mechanistic target of rapamycin, Mammalian target of rapamycin
- Application:
- IHC, WB, IF, ICC, IP
- Concentration:
- 500 ug/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Progen
- Host:
- Rabbit
- Reactivities:
- Canine, Human, Mouse, Rat
- ABP:
- IMP-GEN-14-02 < 3%
- Immunogen:
- Peptide from human mTOR (GTTVPESIHSFIGDGLVKPE)
- Formulation:
- PBS, pH 7.4 with 0.09% sodium azide and 0.5% BSA
- Uniprot:
- P42345
- Synonyms:
- FK506 binding protein 12-rapamycin associated protein 2;FK506-binding protein 12-rapamycin complex-associated protein 1;FKBP-rapamycin associated protein;FKBP12-rapamycin complex-associated protein;FKBP12-rapamycin complex-associated protein 1;FRAP;FRAP1;FRAP2;mammalian target of rapamycin;Mechanistic target of rapamycin;mechanistic target of rapamycin (serine/threonine kinase);RAFT1;rapamycin and FKBP12 target 1;rapamycin associated protein FRAP2;rapamycin target protein 1;RAPT1;serine/threonine-protein kinase mTOR;SKS
- Extra Details:
- Mammalian target of rapamycin (mTOR) is a serine/threonine kinase that plays a key role in protein synthesis, cell growth, proliferation and differentiation. It is inhibited by rapamycin, which has immunosuppressant functions. The 290 kDa protein is highly regulated by growth factors and nutrients like glucose and amino acids. mTOR is involved in several pathways from protein degradation via autophagy to protein synthesis via translation initiation (4EBP), ribosome and lipid synthesis. It is located in vesicles and the cytosol.
- Shipping Conditions:
- Blue Ice