GGTase-IGST, Protein geranylgeranyltransferase type I, rat, recombinant, E. coli

Cannot supply to this region.

SKU:: PR-360
Physical State:: Liquid
Molecular Weight:: A Alpha: 44 kDa, B Beta: 38 kDa
Purity:: >90%
Storage Conditions:: -70[o]C Avoid freeze/thaw cycles. Protect from light.
Supplier:: Jena Bioscience
Extra Details:: GGTase-I (Geranylgeranyltransferase-I) catalyzes the transfer of the farnesyl and geranylgeranyl groups from farnesyl and geranylgeranyl-diphosphate to proteins containing a C-terminal CaaX motif, where 'C' is a conserved cysteine that is the site of farnesyl modification, 'a' is usually an aliphatic amino acid, and 'X' is leucine or phenylalanine. Farnesyltransferase (FT) and GGTase-I are closely related, sharing a common A Alpha subunit and 30% identity in their B Beta subunits. The GST-Tag facilitates the protein`s application in typical GST pull-down assays.