CLK-064
5-Azidomethyl-2'-deoxyuridine (5-AmdU)
Cannot supply to this region.
- SKU:
- CLK-064
- Physical State:
- Solid
- Molecular Weight:
- 283.24 g/mol
- Purity:
- ≥90%
- Storage Conditions:
- RT, 2-8[o]C
- Supplier:
- Jena Bioscience
- ABP:
- No Import Docs
- Extra Details:
- 5-AmdU (5-Azidomethyl-2'-deoxyuridine) can be used as a replacement for BrdU (5-Bromo-2'-deoxyuridine) or the copper-catalyst requiring 5-EdU (5-Ethynyl-2'-deoxyuridine) to measure de novo DNA synthesis during the S-phase of the cell cycle. 5-AmdU is cell permeable and incorporates into peplicating DNA instead of its natural analog thymidine. The resulting azide-functionalized DNA can subsequently be detected via Cu(I)-catalyzed (CuAAC) or Cu(I)-free Click Chemistry that offers the choice tointroduce a Biotin group for subsequent purification tasks (via Alkynes of Biotin or DBCO-functionalized Biotin, respectivly)introduce a fluorescent group for subsequent microscopic imaging (via Alkynes of fluorescent dyes or DBCO-functionalized fluorescent dyes, respectivly).
- Shipping Conditions:
- Ambient