14652
Inostamycin A (Sodium Salt), Antitumor
Size
£650.00
- SKU:
- 14652
- Storage Conditions:
- -20[o]C
- Supplier:
- Funakoshi
- CAS Number:
- 129905-10-8, 1884611-95-3
- Extra Details:
- M.W.: 722.933 (Sodium salt) Purity : >90% (qNMR) Molecular Formula : C38H68O11Na (Sodium salt) Solubility : Soluble in DMSO, DMF, and CHCl3, Poorly soluble in H2O. Inostamycin A is an inhibitor of phosphatidylinositol turnover, supplied as sodium salt. It was reported that this compound inhibited EGF-induced inositol incorporation into inositol lipids in the A431 cell assay system. It was also reported that inhibition of in vitro CDP-DG: inositol transferase activity of the A431 cell membrane, antimicrobial activities against gram-positive bacteria, cytocidal activity against srk-NIH-3T3, and potentiated colchicine cytotoxicity toward KB-C4 cells. In addition, it caused Ms-1 cell to accumulate in the G1 phase and induced morphological apoptosis at high concentration.
- Shipping Conditions:
- Ambient