02966
Benanomicin A, Antifungal via Binding to Mannan
Size
£650.00
- SKU:
- 02966
- Storage Conditions:
- -20[o]C
- Supplier:
- Funakoshi
- CAS Number:
- 116249-65-1
- Extra Details:
- M.W.: 827.74 Purity : > 90％ (HPLC) Molecular Formula : C39H41NO19 Solubility : Soluble in DMSO and DMF, Poorly soluble in MeOH and CHCl3 Insoluble in H2O, Antimicrobial activity (MIC) : Cryptococcus neoformans F-10 0.6~1.25 μg/ml, Cryptococcus laurenti 0.63 μg/ml, Rhodotorula rubra 0.63 μg/ml, Tricosporon cutaneum 1.25~5 μg/ml. Benanomicin A is isolated from Actinomadura sp. MH193-16F4. This compound exhibits excellent therapeutic efficacy against in a Pneumocystis carinii-infected mouse model by intraperitoneal administration at 10mg/kg/day. In addition, this compound also has antimycotic activities via binding to mannan in the cell walls of fungi. It is recently reported that this compound has been utilized to prepare mannan cell walls by the lectin-like functionality of it.
- Shipping Conditions:
- Ambient