Bottromycin A2, Antibacterial (Gram-Positive)

Size

£650.00

SKU:: 00592
Application:: Neutralisation
Storage Conditions:: -20[o]C
Supplier:: Funakoshi
CAS Number:: 15005-62-6
Extra Details:: M.W.: 823.06 Purity : > 80％ (HPLC) Molecular Formula : C42H62N8O7S Solubility : Soluble in H2O, Methanol, and Ether, Insoluble in n-Hexane. Bottromycin A2 has a cyclic peptide structure and shows inhibitory activity against gram-positive bacteria. It is also reported to have low toxicity but strong antibacterial activity against drug-resistant bacteria, such as against MRSA(Methicillin-Resistant Staphylococcus Aureus) and VRE(Vancomycin-Resistant enterococci). The mechanism of Bottromycin A2 is known to inhibit bacterial protein synthesis by binding to the A-site of ribosome and blocking aminoacyl-tRNA binding.