200-75AF
Recombinant Animal-Free Mouse IL-19
Size
£234.00
- SKU:
- 200-75AF
- Additional Names:
- None
- Molecular Weight:
- 17.7
- Purity:
- ≥95
- Source:
- E.coli
- Storage Conditions:
- Sterile water at 0.1 mg/mL
- Supplier:
- FujiFilm Irvine Scientific
- Formulation:
- 10 mM sodium phosphate, 50 mM sodium chloride, pH 7.5
- Format:
- Lyophilized from a 0.2 µm filtered solution
- Species:
- Recombinant Mouse
- Uniprot:
- Q8CJ70
- Extra Details:
- Interleukin-19 (IL-19) is a member of the interleukin 10 (IL-10) cytokine family and is produced by B cells and monocytes. IL-19 binds the interleukin 20 receptor complex (IL-20R) to activate STAT3 signaling. IL-19 induces interleukin 6 (IL-6) and tumor necrosis factor alpha (TNF-α) expression in monocytes, and promotes type 2 T helper (Th2) cell-mediated immune responses. IL-19 production is upregulated in resting monocytes following granulocyte-macrophage colony-stimulating factor (GM-CSF) or lipopolysaccharide (LPS) stimulation.
- Shipping Conditions:
- Ambient