200-70
Recombinant Mouse IL-21
Size
£217.00
- SKU:
- 200-70
- Additional Names:
- None
- Molecular Weight:
- 15.1
- Purity:
- ≥95
- Source:
- E.coli
- Storage Conditions:
- Sterile water at 0.1 mg/mL
- Supplier:
- FujiFilm Irvine Scientific
- Formulation:
- 20 mM Sodium Bicarbonate, pH 8.5
- Format:
- Lyophilized from a 0.2 µm filtered solution
- Species:
- Recombinant Mouse
- Uniprot:
- Q9ES17
- Extra Details:
- Interleukin 21 (IL-21) is a member of the common-gamma chain family of cytokines that are involved in immunoregulation. IL-21 is normally expressed by activated CD4+ T cells. The IL-21 receptor (IL-21R) activates the JAK/STAT signaling pathway and is expressed on T, B, and natural killer (NK) cells. Within the B cell lineage, IL-21 is a switch factor regulating IgG1 and IgG3 antibody production. IL-21 also cooperates with interleukin 4 (IL-4) for the production of multiple antibody classes in B cells. IL-21 has pleiotropic effects on the proliferation, differentiation, and effector functions of B, T, NK, and dendritic cells.
- Shipping Conditions:
- Ambient