200-68
Recombinant Mouse IL-1 β
Size
£217.00
- SKU:
- 200-68
- Additional Names:
- Catabolin, LAF, EP, LEM, MCF
- Molecular Weight:
- 17.5
- Purity:
- ≥95
- Source:
- E.coli
- Storage Conditions:
- Sterile water at 0.1 mg/mL
- Supplier:
- FujiFilm Irvine Scientific
- Formulation:
- 10 mM Sodium Phosphate, pH 7.5
- Format:
- Lyophilized from a 0.2 µm filtered solution
- Species:
- Recombinant Mouse
- Uniprot:
- P10749
- Extra Details:
- Interleukin 1 beta (IL-1β) is a pro-inflammatory cytokine that is produced by monocytes, macrophages, and dendritic cells (DCs). IL-1β signals through the IL-1 receptor, type 1 (IL-1R1) to activate the myeloid differentiation primary response 88 (MYD88) signaling pathway, which contains the cytoplasmic Toll/IL-1 receptor (TIR) domain adapter. IL-1β and the independently regulated IL-1α protein have overlapping proinflammatory activities to induce adhesion molecule expression on epithelial cells, control fever induction, initiate rheumatoid arthritis, and promote septic shock.
- Shipping Conditions:
- Ambient