200-14
Recombinant Mouse G-CSF
Size
£217.00
- SKU:
- 200-14
- Additional Names:
- CSF-3, MGI-1G, GM-CSFβ, pluripoietin
- Molecular Weight:
- 19.1
- Purity:
- ≥95
- Source:
- E.coli
- Storage Conditions:
- Sterile water at 0.1 mg/mL
- Supplier:
- FujiFilm Irvine Scientific
- Formulation:
- 10 mM Sodium Citrate, pH 3.0
- Format:
- Lyophilized from a 0.2 µm filtered solution
- Species:
- Recombinant Mouse
- Uniprot:
- P09920
- Extra Details:
- Granulocyte-colony stimulating factor (G-CSF) is a cytokine that functions as a potent inducer of neutrophilic granulocyte proliferation, terminal differentiation, and activation. G-CSF synthesis occurs in monocyte, macrophage, epithelial, endothelial, and fibroblast cells after activation by bacterial endotoxins, tumor necrosis factor alpha (TNF-α), interleukin 1 (IL-1), or interleukin 17 (IL-17). The functional activity of G-CSF is mediated through the granulocyte colony-stimulating factor receptor (G-CSF-R) to activate JAK/STAT and MAPK signal transduction pathways. G-CSF also promotes neurogenesis and inhibits neuronal apoptosis. Human and mouse G-CSF proteins are cross-reactive.
- Shipping Conditions:
- Ambient