100-85
Recombinant Human IL-13 variant
Size
£217.00
- SKU:
- 100-85
- Additional Names:
- NC30
- Molecular Weight:
- 12.6
- Purity:
- ≥95
- Source:
- E.coli
- Storage Conditions:
- Sterile 10 mM HCl at 0.1 mg/mL
- Supplier:
- FujiFilm Irvine Scientific
- ABP:
- No Import Docs
- Formulation:
- 10 mM Sodium Citrate, pH 3.0
- Format:
- Lyophilized from a 0.2 µm filtered solution
- Species:
- Recombinant Human
- Uniprot:
- P35225
- Extra Details:
- Interleukin 13 (IL-13) is a cytokine secreted from type 2 T helper (Th2) cells. IL-13 has overlapping functions with interleukin 4 (IL-4), including the induction of immunoglobulin E (IgE) secretion from B cells, and the inhibition of interleukin 1 beta (IL-1β), tumor necrosis factor alpha (TNF-α), interleukin 8 (IL-8), and interleukin 6 (IL-6) inflammatory cytokine expression. IL-13 also regulates immune cell inflammation in response to the pathophysiological changes of surrounding non-immune cells. The IL-13 receptor consists of the IL-4Ra and IL-13Ra1 subunits. IL-13 can also bind the IL-13Ra2 receptor with high affinity. IL-13 functions are mediated through the JAK/STAT signaling pathway. Human and mouse IL-13 are cross-reactive.
- Shipping Conditions:
- Ambient