100-187
Recombinant Human FGF-7 / KGF
Size
£217.00
- SKU:
- 100-187
- Additional Names:
- KGF
- Molecular Weight:
- 19
- Purity:
- ≥90
- Source:
- E.coli
- Storage Conditions:
- Sterile water at 0.1 mg/mL (reconstitution at concentrations > 0.1 mg/mL may result in a precipitate)
- Supplier:
- FujiFilm Irvine Scientific
- Formulation:
- 20 mM Sodium Phosphate, 0.5 M Sodium Chloride, pH 7.5
- Format:
- Lyophilized from a 0.2 µm filtered solution
- Species:
- Recombinant Human
- Uniprot:
- P21781
- Extra Details:
- Fibroblast growth factor 7 (FGF-7), also known as keratinocyte growth factor (KGF), is a potent mitogen that regulates epithelial cell migration and differentiation. FGF-7 is produced by mesenchymal cells and binds in high affinity to a splice variant of FGF receptor 2 (FGFR2-IIIb). The mitogenic activity of FGF-7 acts predominantly on keratinocytes, but not on fibroblast or endothelial cells. FGF-7 expression is upregulated after acute and chronic injury, suggesting that FGF-7 functions during the healing of injured epithelial cells. FGF-7 also induces the formation of the apical ectodermal ridge during limb development.
- Shipping Conditions:
- Ambient