100-111
Recombinant Human TNF-α
Size
£111.00
- SKU:
- 100-111
- Additional Names:
- TNFSF2, Cachectin, DIF, Necrosin, Cytotoxin, Cachexin, TNF
- Molecular Weight:
- 17.5
- Purity:
- ≥95
- Source:
- E.coli
- Storage Conditions:
- Sterile water at 0.1 mg/mL
- Supplier:
- FujiFilm Irvine Scientific
- Formulation:
- 10 mM Sodium Phosphate, pH 7.5
- Format:
- Lyophilized from a 0.2 µm filtered solution
- Species:
- Recombinant Human
- Uniprot:
- P01375
- Extra Details:
- Tumor necrosis factor alpha (TNF-α) is an inflammatory cytokine secreted by macrophages, monocytes, neutrophils, T cells, and NK-cells following stimulation by bacterial lipopolysaccharide (LPS). TNF-α signal activation occurs through two receptors, TNFR1 and TNFR2. TNFR1 is expressed on most cell types, unlike TNFR2, which is expressed mainly on immune cells. TNF-α functions to stimulate phagocytosis in macrophages, chemoattract neutrophils, increase insulin resistance, and induce fever.
- Shipping Conditions:
- Ambient