10-7315
Intelliscreen[TM] Polycomb Repressive Complex Inhibitors Mini-Library
Size
£388.00
- SKU:
- 10-7315
- Physical State:
- Supplied as DMSO solution @ 10mM
- Storage Conditions:
- -70[o]C
- Supplier:
- Focus Biomolecules
- Immunogen:
- Chemical Library|Methyltransferase|Ubiquitin ligase
- Extra Details:
- The polycomb-group proteins consist of two classes: Polycomb repressive complex 1 (PRC1) and polycomb repressive complex 2 (PRC2). PRC1 acts as a histone methyltransferase primarily methylating H3K27me3 while PRC2 is a histone ubiquitin ligase acting on histone H2A. Both have important roles in epigenetic gene regulation and are implicated in various disease states because of their role in cellular proliferation-differentiation balance, metabolism, and the immune response.
- Shipping Conditions:
- Dry Ice