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10-5933

O151

Size

POA

SKU:
10-5933
Physical State:
Solid
Molecular Weight:
295.18
Purity:
>98%
Purification:
HPLC Purified
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
CAS Number:
304478-23-7
Immunogen:
DNA
Extra Details:
The DNA base excision repair (BER) pathway, which utilizes DNA glycosylases to initiate repair of specific DNA lesions, is the major pathway for the repair of DNA damage induced by oxidation, alkylation, and deamination.1 The BER pathway is now a validated target in cancer therapeutic development.2 O151 (2763063-26-7) is a selective and potent inhibitor of 8-oxoguanine DNA glycosylase-1 (OGG1) with IC50 of 0.6 uM.3
Shipping Conditions:
Ambient