10-5764
Exatecan mesylate
Size
£158.00
- SKU:
- 10-5764
- Additional Names:
- DX-8951f
- Physical State:
- Solid
- Molecular Weight:
- 531.56
- Purity:
- >98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 169869-90-3
- Immunogen:
- DNA|Topoisomerase
- Extra Details:
- Exatecan mesylate is a hexacyclic, water soluble camptothecin analog exhibiting potent antitumor activity in vitro and in vivo.1 It is a potent topoisomerase I inhibitor displaying antiproliferative activity against 32 malignant cell lines and was shown to be 6 and 28 times more potent than SN-38 and topotecan respectively1. It displays potent cytotoxic effects in various drug-resistant cells.2 Exatecan can be utilized as a cytotoxic payload in the development of novel antibody drug conjugates (ADCs).3
- Shipping Conditions:
- Ambient