10-5723
AqB013
Size
£168.00
- SKU:
- 10-5723
- Physical State:
- Solid
- Molecular Weight:
- 440.52
- Purity:
- >98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 1021869-51-1
- Immunogen:
- Aquaporin
- Extra Details:
- AqB013 is a selective aquaporin-1 and -4 inhibitor (IC50 ~ 20 mM) which acts at the cytoplasmic side of the AQP water pore.1 It blocks cGMP-stimulated human retinal pigment epithelium fluid transport.2 In HT29 colon cancer cells AqB013 restricted migration and invasiveness and prevented endothelial tube formation.3,4 It reduces the invasiveness of U87-MG and U251-MG glioblastoma cells in vitro.5
- Shipping Conditions:
- Ambient