HOIPIN-8

Size

POA

SKU:: 10-5642
Physical State:: Solid
Molecular Weight:: 456.38
Purity:: >98%
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
CAS Number:: 2519537-70-1
Immunogen:: Ubiquitin ligase
Extra Details:: HOIPIN-8 (2519537-70-1) is a potent inhibitor of the linear ubiquitin chain assembly complex (LUBAC), IC50=11 nM.1 HOIPIN-8 suppresses proinflammatory cytokine-induced canonical NF-kB pathway as well as various pathogen-associated molecular pattern-induced antiviral pathways.2 It is a useful tool to assist in unraveling the physiological functions of LUBAC.3,4