10-5638
BG45
Size
£158.00
- SKU:
- 10-5638
- Physical State:
- Solid
- Molecular Weight:
- 214.23
- Purity:
- >98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 926259-99-6
- Immunogen:
- Protein deacetylase
- Extra Details:
- Potent and selective HDAC3 inhibitor (IC50 = 289 nM), IC50s for HDAC1, 2 and 6 = 2, 2.2 and >20 mM respectively.1 Inhibits tumor growth in a mouse xenograft model of human multiple myeloma.1 Downregulates expression of DNA methyltransferase 1.2 Increases expression of synaptic proteins in exogenous AB Beta-treated cells and mice.3 Rescues synaptic damage and neuron loss in APP-transfected cells (15 mM) and APP/PS1 mice (30 mg/kg).4
- Shipping Conditions:
- Ambient