10-5561
KNK437
Size
£158.00
- SKU:
- 10-5561
- Physical State:
- Solid
- Molecular Weight:
- 245.23
- Purity:
- 98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 218924-25-5
- Immunogen:
- HSP (Heat shock protein)
- Extra Details:
- Inhibits constitutive and inducible HSP70 expression in non-stressed1 and heat-stressed2 cancer cells. Blocks the geldanamycin-induced induction of HSP70 and inhibition of TGFB Beta signaling.3 Inhibits leukocyte integrin A Alpha4B Beta7-mediated adhesion of T cells to mucosal addressin cell adhesion molecule 1 (MAdCAM-1) suggesting that HSP70 is essential for B Beta7 integrin signalling.4 Suppresses morphine analgesic tolerance in a rodent model (100 mg/Kg).5
- Shipping Conditions:
- Ambient