PNF1

Size

£168.00

SKU:: 10-5556
Additional Names:: SC-3-149
Physical State:: Solid
Molecular Weight:: 229.24
Purity:: 98%
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
CAS Number:: 10442-95-2
Extra Details:: Novel small molecule inducer of angiogenesis which has been shown to be useful in tissue engineering applications.1 In a sustained release model, PNF1 promoted ingrowth and expansion of microvascular networks surrounding biomaterial implants.2 Its mechanism of action includes induction of TNF-A Alpha followed by TGF-B Beta signaling and subsequent modulation of MMP14 (MT1-MMP) in human microvascular endothelial cells.3,4