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10-5417

Metolazone

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£149.00

SKU:
10-5417
Additional Names:
SR 720-22
Physical State:
Solid
Molecular Weight:
365.83
Purity:
98%
Purification:
HPLC Purified
Storage Conditions:
RT
Supplier:
Focus Biomolecules
CAS Number:
17560-51-9
Immunogen:
UPR (Unfolded protein response)
Extra Details:
Activates mitochondrial unfolded protein response (UPRMT) and -increases C. elegans lifespan.4 Clinically useful diuretic that inhibits the thiazide-sensitive Na+-Cl- cotransporter (NCC) (IC50 = 0.3 uM rat), blocking sodium reabsorption.2,3 Metolazone also inhibits human carbonic anhydrase isoforms VII, XII, and XIII with nanomolar potency.4.
Shipping Conditions:
Ambient