10-5401
CID1067700
Size
£163.00
- SKU:
- 10-5401
- Additional Names:
- ML282
- Physical State:
- Solid
- Molecular Weight:
- 390.48
- Purity:
- 98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 314042-01-8
- Immunogen:
- GTPase|Lysosome
- Extra Details:
- A specific competitive inhibitor of nucleotide binding to Rab7, an endosome-localized small GTPase.1 It interferes with the Rab7-RILP interaction, locking the GTPase in an inactive conformation.2 Impairs B cell class switching and plasma cell survival dampening, the pathogenic autoantibody response in lupus.3 Inhibits the Arf-like small GTPase Arl8b, blocking cellular egress of b-coronaviruses (SARS-CoV-2) which utilize a lysosomal exocytosis pathway.4
- Shipping Conditions:
- Ambient