10-5400
Biotin-isoxazole
Size
£197.00
- SKU:
- 10-5400
- Additional Names:
- B-isox
- Physical State:
- Solid
- Molecular Weight:
- 520.66
- Purity:
- 98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 1377605-22-5
- Immunogen:
- RNA
- Extra Details:
- Exposure of cell or tissue lysates to biotin-isoxazole precipitates hundreds of RNA-binding proteins with significant overlap to the constituents of RNA granules.1,2 In one study roughly 580 nuclear proteins were identified as being precipitated by B-Isox including TAF15, RNA polymerase II (largest subunit), numerous subunits of the mediator complex as well as a variety of enzymes involved in epigenetic modification of histones.3 SR domains were found to be the determinant that facilitates B-Isox precipitation.4 Also allows for the fractionation / isolation of SG-associated proteins and RNA precipitates.5
- Shipping Conditions:
- Ambient