10-5393
Isohelenin
Size
£149.00
- SKU:
- 10-5393
- Additional Names:
- Isoalantolactone
- Physical State:
- Solid
- Molecular Weight:
- 232.32
- Purity:
- 98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 470-17-7
- ABP:
- No Import Docs
- Immunogen:
- Transcription factor
- Extra Details:
- A sesquiterpene lactone isolated from Mexican Indian medicinal plants known to have anti-inflammatory properties. A potent inhibitor of NFB (complete inhibition at 5 M)1 acting via inhibition of IKK6. Isohelenin-mediated NFB inhibition suppresses IL-8 expression2, iNOS expression3 and RANTES biosynthesis4. Displays protective effects in endotoxic shock in rodent models.5 Induces apoptosis in glioma cells.6
- Shipping Conditions:
- Ambient