10-5296
Ascochlorin
Size
£163.00
- SKU:
- 10-5296
- Additional Names:
- Ilicicolin D|NSC 287492
- Physical State:
- Solid
- Molecular Weight:
- 404.93
- Purity:
- >98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 26166-39-2
- Immunogen:
- Cytochrome/MDR
- Extra Details:
- Ascochlorin is a novel isoprenoid phenol isolated from Acremonium egyptiacum and other species.1 It is a novel, specific inhibitor of the mitochondrial cytochrome bc1 complex (mitochondrial respiratory chain complex III) acting at both active sites.2 It induces caspase-independent necroptosis in LPS-stimulated RAW 264.7 macrophages3 resulting in anti-inflammatory effects4. Demonstrates substantial antineoplastic effects in a variety of tumor cell lines and mouse models.5
- Shipping Conditions:
- Ambient