Filgotinib

Size

£163.00

SKU:: 10-5145
Additional Names:: GLPG0634|GS-6034
Physical State:: Solid
Molecular Weight:: 425.50
Purity:: 98%
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
CAS Number:: 1206161-97-8
Immunogen:: Kinase
Extra Details:: Potent and selective JAK1 inhibitor (IC50s=10, 28, 810 and 116 nM for JAK1, JAK2, JAK3 and TYK2 respectively.2 Displays potent anti-inflammatory activity in various models.1,2 Effective as a monotherapy in patients with active rheumatoid arthritis.3 Reverses oncostatin M-mediated inhibition of rat stem Leydig cell differentiation.4