10-5044
GKT-137831
Size
£168.00
- SKU:
- 10-5044
- Additional Names:
- GKT-831|Setanaxib
- Physical State:
- Solid
- Molecular Weight:
- 394.85
- Purity:
- 98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 1218942-37-0
- Immunogen:
- Energy production|Nox (NADH/NADPH oxidase)
- Extra Details:
- NADPH oxidase, NOX1/4 inhibitor (Ki = 100-150 nM).1 Inhibits erastin-stimulated ROS production.2 Potentiates immunotherapy by overcoming cancer-associated fibroblast- mediated CD8+ T-cell exclusion.3 Reduces ROS production in LPS-stimulated platelets in a mouse model.4 Reduces subarachnoid hemorrhage-induced neuronal death.5 Potent inhibitor of experimental liver fibrosis in mouse models.6
- Shipping Conditions:
- Ambient