10-4981
OTUDin3
Size
£168.00
- SKU:
- 10-4981
- Physical State:
- Solid
- Molecular Weight:
- 508.6
- Purity:
- >98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 441290-65-9
- Immunogen:
- DUB (Deubiquitinating enzyme)
- Extra Details:
- OTUDin3 (441290-65-9) is a potent inhibitor of the deubiquitinase OTUD3, a member of the ovarian tumor proteases which plays a key role in tumorigenesis, neurodegeneration, metabolism, and immunity. It inhibited non-small cell lung cancer growth, migration, and invasion via enhancing the ubiquitination and degradation of the anti-apoptotic protein GRP78. OTUDin3 inhibited lung cancer growth in an H1299 mouse xenograft model.
- Shipping Conditions:
- Ambient