Deferasirox

Size

£149.00

SKU:: 10-4949
Additional Names:: ICL670
Physical State:: Solid
Molecular Weight:: 373.36
Purity:: >98%
Purification:: HPLC Purified
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
CAS Number:: 201530-41-8
Immunogen:: Chelator|Protein demethylase
Extra Details:: Clinically useful iron chelator used in long term care of B Beta-thalassemia and other heavily transfused hematological patients.1,2 It has been shown to potent inhibitor of JumonjiC Domain-Containing Histone Demethylases (IC50's = KDM4A(JMJD2A) 4.76 uM, KDM5A(JARID1A) 5.00 uM, KDM6B(JMJD3) 3.95 uM).3 Deferasirox has also been investigated as a potential anticancer agent.4-6